Aliasger Salem, Ph.D., assistant professor of pharmaceutics in the UI College of Pharmacy, has received a two-year $240,000 grant from the National Cancer Institute to optimize vaccines used to treat and prevent solid tumors such as melanoma.
(Media-Newswire.com) - Aliasger Salem, Ph.D., assistant professor of pharmaceutics in the UI College of Pharmacy, has received a two-year $240,000 grant from the National Cancer Institute to optimize vaccines used to treat and prevent solid tumors such as melanoma.
Salem, a member of Holden Comprehensive Cancer Center, will conduct the research with George Weiner, M.D., professor of internal medicine and director of Holden Comprehensive Cancer Center at the UI.
The researchers will develop biodegradable, nanoparticle-based vaccines engineered to release anti-cancer antigens and immunostimulants in such a way as to optimize the desired immune responses in mouse models of melanoma. If this approach proves successful, it may also be applicable to a range of other cancer models including lymphoma, renal carcinoma, colon cancer and pancreatic cancer.
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